Publications

  • Dar RD, Razooky BS, Weinberger LS, Cox CD, Simpson ML. "The Low Noise Limit in Gene Expression." PLoS One. 2015. Published: October 21, 2015.  DOI: 10.1371/journal.pone.0140969
  • Razooky BS, Pai A, Aull K, Rouzine IM, Weinberger LS. "A Hardwired HIV Latency Program."  Cell 2015. Volume 160, Issue 5, p1002–1012, 26 February 2015
  • Rouzine IM, Weinberger AD, Weinberger LS. "An Evolutionary Role for HIV Latency in Enhancing Viral Transmission."  Cell 2015. Volume 160, Issue 5, p1002–1012, 26 February 2015
  • Jung SY, Notton T, Fong E, Shusteff M, Weinberger LS. "Spatial tuning of acoustofluidic pressure nodes by altering net sonic velocity enables high-throughput, efficient cell sorting." Lab on a Chip, 2015 Advance Article. Received 11 Nov 2014, Accepted 23 Dec 2014 First published online 07 Jan 2015
  • Rouzine IM, Razooky BS, Weinberger LS. "Stochastic variability in HIV affects viral eradication." Proc Natl Acad Sci, U S A. 2014 Sep 16;111(37):13251-2. Epub 2014 Sep 8. PMCID: PMC4169906 (Available on 2015/3/16)
  • Notton T, Sardanyes J, Weinberger AD, Weinberger LS. " The case for transmissible antivirals to control population-wide infectious disease." Trends in Biotechnology. Cell Press. Published online July 10 2014. DOI: 10.1016/j.tibtech.2014.06.006                         
  • Dar RD, Hosmane NN, Arkin MR, Siliciano RF, Weinberger LS. "Screening for noise in gene expression identifies drug synergies." Science, 20 June, 2014. Vol. 344 no. 6190 pp. 1392-1396. PMCID: PMC4122234
  • Rouzine IM, Coffin JM, Weinberger LS. "Fifteen Years Later: Hard and Soft Selection Sweeps Confirm a Large Population Number for HIV In Vivo." PLoS Genet. 2014 Feb 20;10(2):e1004179.
  • Fong EJ, Johnston AC, Notton T, Jung SY, Rose KA, Weinberger LS, Shusteff M. "Acoustic focusing with engineered node locations for high-performance microfluidic particle separation."  Analyst. 2014139, 1192-1200
  • Weinberger AD and Weinberger LS.  “Stochastic fate selection in HIV-infected patients.”  Cell, 2013, Oct 24; 153(3), 497-499.
  • Rouzine IM, Weinberger LS. Reply to "Coadaptive Stability of Interfering Particles with HIV-1 When There Is an Evolutionary Conflict." Journal of Virology, 2013 Sep;87(17):9960-2. 
  • Gardner T, Bolovan-Fritts C, Teng M, Redmann V, Kraus T, Sperling R, Moran T, Britt W, Weinberger L, Tortorella D. "Development of a high-throughput assay to measure the neutralization capability of anti-CMV antibodies." Clinical and Vaccine Immunology, April 2013. Vol 20. No. 4, 540-550. PMCID PMC3623408
  • Rouzine IM, Weinberger LS. "Design requirements for interfering particles to maintain coadaptive stability with HIV-1." Journal of Virology, 2013 Feb;87(4):2081-93. doi: 10.1128/JVI.02741-12. PMCID: PMC3571494 
  • Rouzine IM, Weinberger LS. "The quantitative theory of within-host viral evolution." Journal of Statistical Mechanics. (2013) P01009 doi:10.1088/1742-5468/2013/01/P01009

  • Boehm D, Calvanese V, Dar RD, Xing S, Schroeder S, Martins L, Aull K, Li PC, Planelles V, Bradner JE, Zhou MM, F Siliciano RF, Weinberger L, Verdin E, Ott M. "BET bromodomain-targeting compounds reactivate HIV from latency via a Tat-independent mechanism." Cell Cycle 2013 Feb 1;12(3) PMCID: PMC3587446
  • Teng MW, Bolovan-Fritts C, Dar RD, Womack A, Shenk T, Simpson ML, Weinberger LS. “An Endogenous Accelerator for Viral Gene Expression Provides a Fitness Advantage.”  Cell. Volume 151, Issue 7, 1569-1580, 21 December 2012. PMCID: PMC3552493.
  • Dar RD, Razooky BS, Singh A, Trimeloni TV, McCollum JM, Cox CD, Simpson ML, Weinberger LS. Transcriptional burst frequency and burst size are equally modulated across the human genome. Proc Natl Acad Sci U S A. 2012 Oct 23;109(43):17454-9. PMCID: PMC3491463.
  • Razooky B, Gutierrez E, Terry VH, Spina CA, Groisman A, Weinberger, LS. Microwell Devices with Finger-like Channels for Long-Term Imaging of HIV-1 Expression Kinetics in Primary Human Lymphocytes.  Lab on a Chip. 2012. Oct 2;12(21):4305-4312. PMCID: PMC3589574.
  • Singh A, Razooky B, Dar R, Weinberger LS*. The Dynamics of Protein Noise can distinguish between Alternate Sources of Gene-Expression Variability. Nature: Molecular Systems Biology. 2012. Aug 28;8:607. PMCID: PMC3435505.
  • Franz K, Singh A, Weinberger LS. Lentiviral vectors to study stochastic noise in gene expression. Methods in Enzymology. 2011;497:603-22. 
  • Metzger V, Lloyd-Simth JO, Weinberger LS. Autonomous Targeting of Infectious Superspreaders using Engineered Transmissible Therapies. PLoS Computational Biology. 2011 Mar;7(3)e1002015. PMCID: PMC3060167.
  • Razooky B, Weinberger LS. Mapping the architecture of the HIV-1 Tat circuit: A decision-making circuit that lacks bistability and exploits stochastic noise. Methods. 2011. Jan;53(1):68-77. 
  • Singh A, Razooky B, Simpson ML, Weinberger LS. Transcriptional Bursting is a Significant Source of Noise in HIV-1 Gene Expression. Biophysical Journal. 2010. Apr 98(8):L32-34. PMCID: PMC2856162.
  • Weinberger AD, Ribiero, R, Perelson AS and Weinberger LS. Accelerated Immunodeficiency by Anti-CCR5 Treatment in HIV Infection. PLoS Computational Biology. 2009 Aug;5(8):e1000467. PMCID: PMC2715863.
  • Singh A and Weinberger LS. Stochastic Gene Expression as a Molecular Switch for Viral Latency. Current Opinion in Microbiology. 2009 Aug;12(4):460-6. PMCID: PMC2760832.
  • Dasgupta D, Hofmeyr S, Weinberger LS. 2009 National Cyber Leap Year Summit Report.
  • Weinberger LS, Dar RD, Simpson ML. Transient mediated fate-determination in a transcriptional circuit of HIV. Nature Genetics. 2008 Apr;40(4):466-70.
  • Weinberger LS and Shenk T. An HIV feedback resistor: auto-regulatory circuit deactivator and noise buffer. PLoS Biology. 2007 Jan;5(1): e9. PMCID: PMC1717016.
  • Weinberger LS, Burnett JC, Toettcher JE, Arkin AP Schaffer DV. Stochastic Gene Expression in a Lentiviral Positive-Feedback Loop: HIV-1 Tat Fluctuations Drive Phenotypic Diversity. Cell. 2005 Jul 29;122(2):169-82. 
  • Weinberger L.S., Schaffer DV, Arkin AP. Theoretical design of a gene therapy vector to prevent AIDS but maintain HIV-1. Journal of Virology, 2003 Sep;77(18):10028-36. PMCID: PMC224590.
  • Weinberger, L.S. Conditionally replicating viruses as therapeutic strategies against HIV/AIDS. 2004 in Bioethical Perspectives on Genetic Engineering and Biotechnology Laurie Zoloth & Baruch Brody Eds. 2005.
  • Weinberger, L., Elucidating a novel stochastic mechanism in HIV-1 Tat transactivation and harnessing it for AIDS therapy. 2004. Ph.D. Dissertation. University of California Berkeley.
  • Rosen HR, Ribeiro RR, Weinberger L, Wolf S, Chung M, Gretch DR, Perelson AS. Early hepatitis C viral kinetics correlate with long-term outcome in patients receiving high dose induction followed by combination interferon and ribavirin therapy. J. Hepatol. 2002 Jul;37(1):124-30.
  • Mohri H, Perelson AS, Tung K, Ribeiro RM, Ramratnam B, Markowitz M, Kost R, Hurley A, Weinberger L, Cesar D, Hellerstein MK, Ho DD. Increased turnover of T lymphocytes in HIV-1 infection and its reduction by antiretroviral therapy. J. Exp. Med. 2001 Nov 5;194(9):1277-87.
  • Shiratori Y, Perelson AS, Weinberger L, Imazeki F, Yokosuka O, Nakata R, Ihori M, Hirota K, Ono N, Kuroda H, Motojima T, Nishigaki M, Omata M. Different turnover rate of hepatitis C virus clearance by different treatment regimen using interferon-beta. J. Hepatol. 2000 Aug;33(2):313-22.
  • Jin X, Bauer DE, Tuttleton SE, Lewin S, Gettie A, Blanchard J, Irwin CE, Safrit JT, Mittler J, Weinberger L, Kostrikis LG, Zhang L, Perelson AS, Ho DD. Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques. J. Exp. Med. 1999 Mar 15;189(6):991-8.