Publications

Original Research Articles

  1. Girasole AE, Lum MY, Nathaniel D, Bair-Marshall CJ, Guenthner CJ, Luo L, Kreitzer AC, Nelson AB. (2018) A subpopulation of striatal neurons mediates levodopa-induced dyskinesia. Neuron 97(4):787-795.
  2. Owen SF, Berke JD, Kreitzer AC. (2018) Fast-spiking interneurons supply feedforward control of bursting, calcium, and plasticity for efficient learning. Cell 172(4):683–695.
  3. Kharkwal G, Brami-Cherrier K, Lizardi-Ortiz JE, Nelson AB, Ramos M, Del Barrio D, Sulzer D, Kreitzer AC, Borrelli E. (2016) Parkinsonism driven by antipsychotics originates from dopaminergic control of striatal cholinergic interneurons. Neuron 91(1):67–78.
  4. Lee HJ, Weitz AJ, Bernal-Casas D, Duffy BA, Choy M, Kravitz AV, Kreitzer AC, Lee JH. (2016) Activation of direct and indirect pathway medium spiny neurons drives distinct brain-wide responses. Neuron 91(2):412–424.
  5. Parker PR, Lalive AL, Kreitzer AC. (2016) Pathway-specific remodeling of thalamostriatal synapses in parkinsonian mice. Neuron 89(4):734–740.
  6. Roseberry TK, Lee AM, Lalive AL, Wilbrecht L, Bonci A, Kreitzer AC. (2016) Cell-type-specific control of brainstem locomotor circuits by basal ganglia. Cell 164(3):526–537
  7. Nelson AB, Bussert TG, Kreitzer AC, Seal RP. (2014) Striatal cholinergic neurotransmission requires VGLUT3. J. Neurosci. 34:8772–8777.
  8. Nelson AB, Hammack N, Yang CF, Shah NM, Seal RP, Kreitzer AC. (2014) Striatal cholinergic interneurons drive GABA release from dopamine terminals. Neuron 82:63–70.
  9. Wall NR1, De La Parra M, Callaway EM, Kreitzer AC. Differential innervation of direct- and indirect-pathway striatal projection neurons. Neuron. 2013 Jul 24;79(2):347-60.
  10. Kravitz AV, Owen SF, Kreitzer AC. (2013) Optogenetic identification of striatal projection neuron subtypes during in vivo recordings. Brain Res. 1511:21–32.
  11. Suberbielle E, Sanchez PE, Kravitz AV, Wang X, Ho K, Eilertson K, Devidze N, Kreitzer AC, Mucke L. (2013). Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β. Nat. Neurosci. 16:613–621.
  12. Freeze BS, Kravitz AV, Hammack N, Berke JD, Kreitzer AC. (2013). Control of basal ganglia output by direct and indirect pathway projection neurons. J. Neurosci. 33:18531–18539.
  13. Ring KL, Tong LM, Balestra ME, Javier R, Andrews-Zwilling Y, Li G, Walker D, Zhang WR, Kreitzer AC, Huang Y. (2012). Direct reprogramming of mouse and human fibroblasts into multipotent neural stem cells with a single factor. Cell Stem Cell 11:100–109.
  14. Kravitz AV, Kreitzer AC. (2012). Striatal mechanisms underlying movement, reinforcement, and punishment. Physiology 27:167–177.
  15. Gittis AH, Kreitzer AC. (2012). Striatal microcircuitry and movement disorders. Trends Neurosci. 35:577–564.
  16. Nelson AB, Hang GB, Grueter BA, Pascoli V, Luscher C, Malenka RC, Kreitzer AC (2012). A comparison of striatal-dependent behaviors in wild-type and hemizygous Drd1a and Drd2 BAC transgenic mice. Journal of Neuroscience 32(27):9119-9123.
  17. Kravitz AV, Tye LD, Kreitzer AC (2012). Distinct roles for direct and indirect pathway striatal neurons in reinforcement. Nature Neuroscience 15:816–818.
  18. Verret L, Mann EO, Hang GB, Barth AMI, Cobos I, Ho K, Devidze N, Masliah E, Kreitzer AC, Mody I, Mucke L, Palop JJ (2012). Inhibitory interneuron deficit links altered network activity and cognitive dysfunction in Alzheimer model. Cell 149:708-721.
  19. Harwell CC, Parker PR, Gee SM, Okada A, McConnell SK, Kreitzer AC, Kriegstein AR (2012). Sonic hedgehog expression in corticofugal projection neurons directs cortical microcircuit formation. Neuron 73:1116-1126.
  20. Lerner TN, Kreitzer AC (2012). RGS4 is required for dopaminergic control of striatal LTD and susceptibility to parkinsonian motor deficits. Neuron 73:347-359
  21. Gittis AH, Leventhal DK, Fensterheim BA, Pettibone JR, Berke JD, Kreitzer AC (2011). Selective inhibition of striatal fast-spiking interneurons causes dyskinesias. J Neurosci 31(44):15727-31.
  22. Gittis AH, Hang GB, LaDow ES, Shoenfeld LM, Atallah BV, Finkbeiner S, Kreitzer AC (2011). Rapid target-specific remodeling of fast-spiking inhibitory circuits after loss of dopamine. Neuron 71:858-868.
  23. Kravitz AV, Freeze BS, Parker PRL, Kay K, Thwin MT, Deisseroth K, Kreitzer AC (2010). Regulation of parkinsonian motor behaviors by optogenetic control of basal ganglia circuitry. Nature 466:622-626.
  24. Gittis AH, Nelson AB, Thwin AT, Palop JJ, Kreitzer AC (2010). Distinct roles of GABAergic interneurons in the regulation of striatal output pathways. J Neurosci 30(6):2223-2234.
  25. Lerner TN, Horne EA, Stella N, Kreitzer AC (2010). Striatal endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists. J Neurosci 30(6):2160-4.
  26. Palop JJ, Chin J, Roberson ED, Wang J, Thwin MT, Bien-Ly N, Yoo J, Ho KO, Yu G, Kreitzer A, Finkbeiner S, Noebels JL, Mucke L (2007). Aberrant excitatory neuronal activity and compensatory remodeling of inhibitory hippocampal circuits in mouse models of Alzheimer’s Disease. Neuron 55:697-711.
  27. Singla S, Kreitzer AC, Malenka RC (2007). Mechanisms for synapse specificity during striatal long-term depression. J. Neurosci .27:5260-5264.
  28. Kreitzer AC, Malenka RC (2007). Endocannabinoid-mediated rescue of striatal LTD and motor deficits in Parkinsonís disease models. Nature 445:643-647.
  29. Kreitzer AC, Malenka RC (2005). Dopamine modulation of state-dependent endocannabinoid release and LTD in the striatum. J. Neurosci .25:10537-10545.
  30. Foster KF, Kreitzer AC, Regehr WG (2002). Interaction of postsynaptic receptor saturation with presynaptic mechanisms produces a reliable synapse. Neuron 36:1115-1126.
  31. Kreitzer AC, Carter AG, Regehr WG (2002). Inhibition of interneuron firing extends the spread of endocannabinoid signaling in the cerebellum. Neuron 34:787-796.
  32. Kreitzer AC, Regehr WG (2001). Cerebellar depolarization-induced suppression of inhibition is mediated by endogenous cannabinoids. J. Neurosci. RC174:1-5.
  33. Kreitzer AC, Regehr WG (2001). Retrograde inhibition of presynaptic calcium influx by endogenous cannabinoids at excitatory synapses onto Purkinje cells. Neuron 29:717-727.
  34. Kreitzer AC, Gee KR, Archer EA, Regehr WG (2000). Monitoring presynaptic calcium dynamics in projection fibers by in vivo loading of a novel calcium indicator. Neuron 27:25-32.
  35. Dittman JS, Kreitzer AC, Regehr WG (2000). Interplay between facilitation, depression, and residual calcium at three presynaptic terminals. J. Neurosci. 20:1374-1385.
  36. Kreitzer AC, Regehr WG (2000). Modulation of transmission during trains at a cerebellar synapse. J. Neurosci. 20:1348-1357.