yamanaka lab

2018
Rand T, Sutou K, Tanabe K, Jeong D, Nomura M, Kitaoka F, Tomoda E, Narita M, Nakamura M, Nakamura M, Watanabe A, Rulifson E, Yamanaka S, Takahashi K. (2018) MYC releases early reprogrammed human cells from proliferation pause via retinoblastoma protein inhibition. Cell Reports. 23: 361.

2017
Sugiyama H, Takahashi K, Yamamoto T, Iwasaki M, Narita M, Nakamura M, Rand TA, Nakagashi M, Watanabe A, Yamanaka S. (2016) Nat1 promotes translation of specific proteins that induce differentiation of mouse embryonic stem cells. Proc Natl Acad Sci U S A. 114:340.

2016
Kime C, Sakaki-Yumoto M, Goodrich L, Hayashi Y, Sami S, Derynck R, Asahi M, Panning B, Yamanaka S, Tomoda K. (2016) Autotaxin-mediated lipid signaling intersects with LIF and BMP signaling to promote the naive pluripotency transcription factor program. Proc Natl Acad Sci U S A. 113:12478.

Hayashi Y, Hsiao EC, Sami S, Lancero M, Schlieve CR, Nguyen T, Yano K, Nagahashi A, Ikeya M, Matsumoto Y, Nishimura K, Fukuda A, Hisatake K, Tomoda K, Asaka I, Toguchida J, Conklin BR, Yamanaka S. (2016) BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence. Proc Natl Acad Sci U S A. 113:13057.

2015
Kime C, Rand T, Ivey, K, Srivastava D, Yamanaka S, Tomoda K. (2015) Practical Integration-Free Episomal Methods for Generating Human Induced Pluripotent Stem Cells. Current Protocols in Human Genetics. 87: 21.2.1.

Hayashi Y, Caboni L, Das D, Yumoto F, Clayton T, Deller M, Nguyen P, Farr C, Chiu H, Miller M, Elsliger M, Deacon A, Godzik A, Lesley S, Tomoda K, Conklin B, Wilson I, Yamanaka S, Fletterick R. (2015) Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells. . Proc Natl Acad Sci U S A. 112:4666.

2014
Spencer CL, Baba S, Nakamura K, Hua EA, Sears MA, Fu CC, Zhang J, Balijepalli S, Tomada K, Hayashi Y, Lizarraga P, Wojciak J, Scheinman MM, Aalto-Setala K, Makielski JC, January CT, Healy KE, Yamanaka S, Conklin BR. (2014) Calcium transients closely reflect prolonged action potentials in iPSC models of inherited cardiac arrhythmia. Stem Cell Reports. 4(2):269-81.

Araoka T, Mae S, Kurose Y, Uesugi M, Ohta A, Yamanaka S, Osafune K. (2014) Efficient and Rapid Induction of Human iPSCs/ESCs into Nephrogenic Intermediate Mesoderm Using Small Molecule-Based Differentiation Methods. PLoS One 9: e84881 PMC3893162

Bershteyn M, Hayashi Y, Desachy G, Hsiao EC, Sami S, Tsang KM, Weiss LA, Kriegstein AR, Yamanaka S, Wynshaw-Boris A. (2014) Cell-autonomous correction of ring chromosomes in human induced pluripotent stem cells. Nature Epub ahead of print

Nakagawa M, Taniguchi Y, Senda S, Takizawa N, Ichisaka T, Asano K, Morizane A, Doi D, Takahashi J, Nishizawa M, Yoshida Y, Toyoda T, Osafune K, Sekiguchi K, Yamanaka S. (2014) A novel efficient feeder-free culture system for the derivation of human induced pluripotent stem cells. Sci Rep 4: 3594 PMC3884228

2013
Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H. (2013) Response to comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells". Sci Transl Med 5: 188lr2

Fujishiro SH, Nakano K, Mizukami Y, Azami T, Arai Y, Matsunari H, Ishino R, Nishimura T, Watanabe M, Abe T, Furukawa Y, Umeyama K, Yamanaka S, Ema M, Nagashima H, Hanazono Y. (2013) Generation of naive-like porcine-induced pluripotent stem cells capable of contributing to embryonic and fetal development. Stem Cells Dev 22: 473-82 PMC3549629

Kamakura T, Makiyama T, Sasaki K, Yoshida Y, Wuriyanghai Y, Chen J, Hattori T, Ohno S, Kita T, Horie M, Yamanaka S, Kimura T. (2013) Ultrastructural maturation of human-induced pluripotent stem cell-derived cardiomyocytes in a long-term culture. Circ J 77: 1307-14

Kaneko S, Yamanaka S. (2013) To be immunogenic, or not to be: that's the iPSC question. Cell Stem Cell 12: 385-6

Kondo T, Asai M, Tsukita K, Kutoku Y, Ohsawa Y, Sunada Y, Imamura K, Egawa N, Yahata N, Okita K, Takahashi K, Asaka I, Aoi T, Watanabe A, Watanabe K, Kadoya C, Nakano R, Watanabe D, Maruyama K, Hori O, Hibino S, Choshi T, Nakahata T, Hioki H, Kaneko T, Naitoh M, Yoshikawa K, Yamawaki S, Suzuki S, Hata R, Ueno S, Seki T, Kobayashi K, Toda T, Murakami K, Irie K, Klein WL, Mori H, Asada T, Takahashi R, Iwata N, Yamanaka S, Inoue H. (2013) Modeling Alzheimer's disease with iPSCs reveals stress phenotypes associated with intracellular Abeta and differential drug responsiveness. Cell Stem Cell 12: 487-96

Koyanagi-Aoi M, Ohnuki M, Takahashi K, Okita K, Noma H, Sawamura Y, Teramoto I, Narita M, Sato Y, Ichisaka T, Amano N, Watanabe A, Morizane A, Yamada Y, Sato T, Takahashi J, Yamanaka S. (2013) Differentiation-defective phenotypes revealed by large-scale analyses of human pluripotent stem cells. Proc Natl Acad Sci U S A 110: 20569-74 PMC3870695

Mae S, Shono A, Shiota F, Yasuno T, Kajiwara M, Gotoda-Nishimura N, Arai S, Sato-Otubo A, Toyoda T, Takahashi K, Nakayama N, Cowan CA, Aoi T, Ogawa S, McMahon AP, Yamanaka S, Osafune K. (2013) Monitoring and robust induction of nephrogenic intermediate mesoderm from human pluripotent stem cells. Nat Commun 4: 1367

Matsumoto Y, Hayashi Y, Schlieve CR, Ikeya M, Kim H, Nguyen TD, Sami S, Baba S, Barruet E, Nasu A, Asaka I, Otsuka T, Yamanaka S, Conklin BR, Toguchida J, Hsiao EC. (2013) Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation. Orphanet J Rare Dis 8: 190 PMC3892046

Miki K, Yoshida Y, Yamanaka S. (2013) Making steady progress on direct cardiac reprogramming toward clinical application. Circ Res 113: 13-5

Nagata N, Yamanaka S. (2013) Young researchers in Japan. Science 340: 407

Ohta S, Nishida E, Yamanaka S, Yamamoto T. (2013) Global splicing pattern reversion during somatic cell reprogramming. Cell Rep 5: 357-66

Okano H, Nakamura M, Yoshida K, Okada Y, Tsuji O, Nori S, Ikeda E, Yamanaka S, Miura K. (2013) Steps toward safe cell therapy using induced pluripotent stem cells. Circ Res 112: 523-33

Okita K, Yamakawa T, Matsumura Y, Sato Y, Amano N, Watanabe A, Goshima N, Yamanaka S. (2013) An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells. Stem Cells 31: 458-66

Pandey RR, Tokuzawa Y, Yang Z, Hayashi E, Ichisaka T, Kajita S, Asano Y, Kunieda T, Sachidanandam R, Chuma S, Yamanaka S, Pillai RS. (2013) Tudor domain containing 12 (TDRD12) is essential for secondary PIWI interacting RNA biogenesis in mice. Proc Natl Acad Sci USA 110: 16492-7 PMC3799322

Takahashi K, Yamanaka S. (2013) Induced pluripotent stem cells in medicine and biology. Development 140: 2457-61

Takahashi K, Yamanaka S (2013) Induced pluripotent stem cells. In Stem Cells: From Biology to Therapy (Current Topics from the Encyclopedia of Molecular Cell Biology and Molecular Medicine) (Meyers RA, eds.) 1st Ed., pp. 41-62, Wiley-Blackwell

Tanabe K, Nakamura M, Narita M, Takahashi K, Yamanaka S. (2013) Maturation, not initiation, is the major roadblock during reprogramming toward pluripotency from human fibroblasts. Proc Natl Acad Sci USA 110: 12172-9 PMC3725041

Veraitch O, Kobayashi T, Imaizumi Y, Akamatsu W, Sasaki T, Yamanaka S, Amagai M, Okano H, Ohyama M. (2013) Human induced pluripotent stem cell-derived ectodermal precursor cells contribute to hair follicle morphogenesis in vivo. J Invest Dermatol 133: 1479-88 Epub 2013 Jan 15

Watanabe A, Yamada Y, Yamanaka S. (2013) Epigenetic regulation in pluripotent stem cells: a key to breaking the epigenetic barrier. Philos Trans R Soc Lond B Biol Sci 368: 20120292 PMC3539367

Worringer KA, Rand TA, Hayashi Y, Sami S, Takahashi K, Tanabe K, Narita M, Srivastava D, Yamanaka S. (2013) The let-7/LIN-41 Pathway Regulates Reprogramming to Human Induced Pluripotent Stem Cells by Controlling Expression of Prodifferentiation Genes. Cell Stem Cell 14: 40-52

Yamana R, Iwasaki M, Wakabayashi M, Nakagawa M, Yamanaka S, Ishihama Y. (2013) Rapid and Deep Profiling of Human Induced Pluripotent Stem Cell Proteome by One-shot NanoLC-MS/MS Analysis with Meter-scale Monolithic Silica Columns. J Proteome Res 12: 214-21 Epub 2012 Dec 4

Yamanaka S. (2013) Shinya Yamanaka: purveyor of pluripotency. Interview by Ruth Williams. Circ Res 112: 233-5 Epub 2012 Dec 10

Yamanaka S. (2013) The winding road to pluripotency (Nobel Lecture). Angew Chem Int Ed Engl 52: 13900-9 Epub 2013 Nov 19

Yamashita A, Liu S, Woltjen K, Thomas B, Meng G, Hotta A, Takahashi K, Ellis J, Yamanaka S, Rancourt DE. (2013) Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells. Sci Rep 3: 1978 PMC3680803

2012
Asaka I, Yamanaka S. (2012) Human Stem Cell Manual: Second Edition; Chapter 10 Human Induced Pluripotent Stem Cell Generation: Conventional Method 143-163; Chapter 11 Integration-Free Method for the Generation of Human Induced Pluripotent Stem Cells 165-173; Chapter 12 Methods for Evaluating Human Induced Pluripotent Stem Cells 175-184

Blanpain C, Daley GQ, Hochedlinger K, Passegue E, Rossant J, Yamanaka S. (2012) Stem cells assessed. Nat Rev Mol Cell Biol 13: 471-6

Egawa N, Kitaoka S, Tsukita K, Naitoh M, Takahashi K, Yamamoto T, Adachi F, Kondo T, Okita K, Asaka I, Aoi T, Watanabe A, Yamada Y, Morizane A, Takahashi J, Ayaki T, Ito H, Yoshikawa K, Yamawaki S, Suzuki S, Watanabe D, Hioki H, Kaneko T, Makioka K, Okamoto K, Takuma H, Tamaoka A, Hasegawa K, Nonaka T, Hasegawa M, Kawata A, Yoshida M, Nakahata T, Takahashi R, Marchetto MC, Gage FH, Yamanaka S, Inoue H. (2012) Drug screening for ALS using patient-specific induced pluripotent stem cells. Sci Transl Med 4: 145ra104

Hayashi Y, Saitou M, Yamanaka S. (2012) Germline development from human pluripotent stem cells toward disease modeling of infertility. Fertil Steril 97: 1250-9

Kajiwara M, Aoi T, Okita K, Takahashi R, Inoue H, Takayama N, Endo H, Eto K, Toguchida J, Uemoto S, Yamanaka S. (2012) Donor-dependent variations in hepatic differentiation from human-induced pluripotent stem cells. Proc Natl Acad Sci USA 109: 12538-43 PMC3411998

Kobayashi Y, Okada Y, Itakura G, Iwai H, Nishimura S, Yasuda A, Nori S, Hikishima K, Konomi T, Fujiyoshi K, Tsuji O, Toyama Y, Yamanaka S, Nakamura M, Okano H. (2012) Pre-Evaluated Safe Human iPSC-Derived Neural Stem Cells Promote Functional Recovery after Spinal Cord Injury in Common Marmoset without Tumorigenicity. PLoS One 7: e52787 PMC3531369

Lahti AL, Kujala VJ, Chapman H, Koivisto AP, Pekkanen-Mattila M, Kerkela E, Hyttinen J, Kontula K, Swan H, Conklin BR, Yamanaka S, Silvennoinen O, Aalto-Setala K. (2012) Model for long QT syndrome type 2 using human iPS cells demonstrates arrhythmogenic characteristics in cell culture. Dis Model Mech 5: 220-30 PMC3291643

Miki K, Uenaka H, Saito A, Miyagawa S, Sakaguchi T, Higuchi T, Shimizu T, Okano T, Yamanaka S, Sawa Y. (2012) Bioengineered myocardium derived from induced pluripotent stem cells improves cardiac function and attenuates cardiac remodeling following chronic myocardial infarction in rats. Stem Cells Transl Med 1: 430-7

Takahashi K, Yamanaka S. (2012) Induced Pluripotent Stem Cells. Encyclopedia of Molecular Cell Biology and Molecular Medicine. doi: 10.1002/3527600906.mcb.201100023

Tanaka T, Takahashi K, Yamane M, Tomida S, Nakamura S, Oshima K, Niwa A, Nishikomori R, Kambe N, Hara H, Mitsuyama M, Morone N, Heuser JE, Yamamoto T, Watanabe A, Sato-Otsubo A, Ogawa S, Asaka I, Heike T, Yamanaka S, Nakahata T, Saito MK. (2012) Induced pluripotent stem cells from CINCA syndrome patients as a model for dissecting somatic mosaicism and drug discovery. Blood 120: 1299-308

Tomoda K, Takahashi K, Leung K, Okada A, Narita M, Yamada NA, Eilertson KE, Tsang P, Baba S, White MP, Sami S, Srivastava D, Conklin BR, Panning B, Yamanaka S. (2012) Derivation conditions impact X-inactivation status in female human induced pluripotent stem cells. Cell Stem Cell 11: 91-9 PMC3396435

Yamanaka S. (2012) Induced pluripotent stem cells: past, present, and future. Cell Stem Cell 10: 678-84

Yoshida Y, Yamanaka S. (2012) An emerging strategy of gene therapy for cardiac disease. Circ Res 111: 1108-10

Yoshida Y, Yamanaka S. (2012) Labor pains of new technology: direct cardiac reprogramming. Circ Res 111: 3-4

2011
Amps K, Andrews PW, Anyfantis G, Armstrong L, Avery S, Baharvand H, Baker J, Baker D, Munoz MB, Beil S, Benvenisty N, Ben-Yosef D, Biancotti JC, Bosman A, Brena RM, Brison D, Caisander G, Camarasa MV, Chen J, Chiao E, Choi YM, Choo AB, Collins D, Colman A, Crook JM, Daley GQ, Dalton A, De Sousa PA, Denning C, Downie J, Dvorak P, Montgomery KD, Feki A, Ford A, Fox V, Fraga AM, Frumkin T, Ge L, Gokhale PJ, Golan-Lev T, Gourabi H, Gropp M, Lu G, Hampl A, Harron K, Healy L, Herath W, Holm F, Hovatta O, Hyllner J, Inamdar MS, Irwanto AK, Ishii T, Jaconi M, Jin Y, Kimber S, Kiselev S, Knowles BB, Kopper O, Kukharenko V, Kuliev A, Lagarkova MA, Laird PW, Lako M, Laslett AL, Lavon N, Lee DR, Lee JE, Li C, Lim LS, Ludwig TE, Ma Y, Maltby E, Mateizel I, Mayshar Y, Mileikovsky M, Minger SL, Miyazaki T, Moon SY, Moore H, Mummery C, Nagy A, Nakatsuji N, Narwani K, Oh SK, Oh SK, Olson C, Otonkoski T, Pan F, Park IH, Pells S, Pera MF, Pereira LV, Qi O, Raj GS, Reubinoff B, Robins A, Robson P, Rossant J, Salekdeh GH, et al. (2011) Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage. Nat Biotechnol 29: 1132-44 PMC3454460

Denda K, Nakao-Wakabayashi K, Okamoto N, Kitamura N, Ryu JY, Tagawa Y, Ichisaka T, Yamanaka S, Komada M. (2011) Nrk, an X-linked protein kinase in the germinal center kinase family, is required for placental development and fetoplacental induction of labor. J Biol Chem 286: 28802-10 PMC3190688

Fujiwara M, Yan P, Otsuji TG, Narazaki G, Uosaki H, Fukushima H, Kuwahara K, Harada M, Matsuda H, Matsuoka S, Okita K, Takahashi K, Nakagawa M, Ikeda T, Sakata R, Mummery CL, Nakatsuji N, Yamanaka S, Nakao K, Yamashita JK. (2011) Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A. PLoS One 6: e16734 PMC3043062

Higashi H, Brustle O, Daley GQ, Yamanaka S. (2011) The nomenclature system should be sustainable, but also practical. Cell Stem Cell 8: 606-7

Hiratsuka M, Uno N, Ueda K, Kurosaki H, Imaoka N, Kazuki K, Ueno E, Akakura Y, Katoh M, Osaki M, Kazuki Y, Nakagawa M, Yamanaka S, Oshimura M. (2011) Integration-free iPS cells engineered using human artificial chromosome vectors. PLoS One 6: e25961 PMC3187830

Inoue H, Yamanaka S. (2011) The use of induced pluripotent stem cells in drug development. Clin Pharmacol Ther 89: 655-61

Iwabuchi KA, Yamakawa T, Sato Y, Ichisaka T, Takahashi K, Okita K, Yamanaka S. (2011) ECAT11/L1td1 is enriched in ESCs and rapidly activated during iPSC generation, but it is dispensable for the maintenance and induction of pluripotency. PLoS One 6: e20461 PMC3102727

Maekawa M, Yamaguchi K, Nakamura T, Shibukawa R, Kodanaka I, Ichisaka T, Kawamura Y, Mochizuki H, Goshima N, Yamanaka S. (2011) Direct reprogramming of somatic cells is promoted by maternal transcription factor Glis1. Nature 474: 225-9

Maekawa M, Yamanaka S. (2011) Glis1, a unique pro-reprogramming factor, may facilitate clinical applications of iPSC technology. Cell Cycle 10: 3613-4

Nakamura T, Nakagawa M, Ichisaka T, Shiota A, Yamanaka S. (2011) Essential roles of ECAT15-2/Dppa2 in functional lung development. Mol Cell Biol 31: 4366-78 PMC3209334

Nori S, Okada Y, Yasuda A, Tsuji O, Takahashi Y, Kobayashi Y, Fujiyoshi K, Koike M, Uchiyama Y, Ikeda E, Toyama Y, Yamanaka S, Nakamura M, Okano H. (2011) Grafted human-induced pluripotent stem-cell-derived neurospheres promote motor functional recovery after spinal cord injury in mice. Proc Natl Acad Sci USA 108: 16825-30 PMC3189018

Ohta S, Imaizumi Y, Okada Y, Akamatsu W, Kuwahara R, Ohyama M, Amagai M, Matsuzaki Y, Yamanaka S, Okano H, Kawakami Y. (2011) Generation of human melanocytes from induced pluripotent stem cells. PLoS One 6: e16182 PMC3020956

Okita K, Matsumura Y, Sato Y, Okada A, Morizane A, Okamoto S, Hong H, Nakagawa M, Tanabe K, Tezuka K, Shibata T, Kunisada T, Takahashi M, Takahashi J, Saji H, Yamanaka S. (2011) A more efficient method to generate integration-free human iPS cells. Nat Methods 8: 409-12

Okita K, Nagata N, Yamanaka S. (2011) Immunogenicity of induced pluripotent stem cells. Circ Res 109: 720-1

Okita K, Yamanaka S. (2011) Induced pluripotent stem cells: opportunities and challenges. Philos Trans R Soc Lond B Biol Sci 366: 2198-207 PMC3130417

Sakurai H, Yamanaka S. (2011) [Research for cell therapy by induced pluripotent stem cell]. Nihon Rinsho 69: 2114-8

Uosaki H, Fukushima H, Takeuchi A, Matsuoka S, Nakatsuji N, Yamanaka S, Yamashita JK. (2011) Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression. PLoS One 6: e23657 PMC3158088

Wang YC, Nakagawa M, Garitaonandia I, Slavin I, Altun G, Lacharite RM, Nazor KL, Tran HT, Lynch CL, Leonardo TR, Liu Y, Peterson SE, Laurent LC, Yamanaka S, Loring JF. (2011) Specific lectin biomarkers for isolation of human pluripotent stem cells identified through array-based glycomic analysis. Cell Res 21: 1551-63 PMC3364725

Yagi T, Ito D, Okada Y, Akamatsu W, Nihei Y, Yoshizaki T, Yamanaka S, Okano H, Suzuki N. (2011) Modeling familial Alzheimer's disease with induced pluripotent stem cells. Hum Mol Genet 20: 4530-9

Yahata N, Asai M, Kitaoka S, Takahashi K, Asaka I, Hioki H, Kaneko T, Maruyama K, Saido TC, Nakahata T, Asada T, Yamanaka S, Iwata N, Inoue H. (2011) Anti-Abeta drug screening platform using human iPS cell-derived neurons for the treatment of Alzheimer's disease. PLoS One 6: e25788 PMC3184175

Yamanaka S. (2011) Genome-sequencing anniversary. Of mice and humans. Science 331: 873

Yoshida Y, Yamanaka S. (2011) iPS cells: a source of cardiac regeneration. J Mol Cell Cardiol 50: 327-32

2010
Egusa H, Okita K, Kayashima H, Yu G, Fukuyasu S, Saeki M, Matsumoto T, Yamanaka S, Yatani H. (2010) Gingival fibroblasts as a promising source of induced pluripotent stem cells. PLoS One 5: e12743 PMC2939066

Espejel S, Roll GR, McLaughlin KJ, Lee AY, Zhang JY, Laird DJ, Okita K, Yamanaka S, Willenbring H. (2010) Induced pluripotent stem cell-derived hepatocytes have the functional and proliferative capabilities needed for liver regeneration in mice. J Clin Invest 120: 3120-6 PMC2929736

Homma K, Sone M, Taura D, Yamahara K, Suzuki Y, Takahashi K, Sonoyama T, Inuzuka M, Fukunaga Y, Tamura N, Itoh H, Yamanaka S, Nakao K. (2010) Sirt1 plays an important role in mediating greater functionality of human ES/iPS-derived vascular endothelial cells. Atherosclerosis 212: 42-7

Imamura M, Aoi T, Tokumasu A, Mise N, Abe K, Yamanaka S, Noce T. (2010) Induction of primordial germ cells from mouse induced pluripotent stem cells derived from adult hepatocytes. Mol Reprod Dev 77: 802-11

Kaichi S, Hasegawa K, Takaya T, Yokoo N, Mima T, Kawamura T, Morimoto T, Ono K, Baba S, Doi H, Yamanaka S, Nakahata T, Heike T. (2010) Cell line-dependent differentiation of induced pluripotent stem cells into cardiomyocytes in mice. Cardiovasc Res 88: 314-23

Kazuki Y, Hiratsuka M, Takiguchi M, Osaki M, Kajitani N, Hoshiya H, Hiramatsu K, Yoshino T, Kazuki K, Ishihara C, Takehara S, Higaki K, Nakagawa M, Takahashi K, Yamanaka S, Oshimura M. (2010) Complete genetic correction of ips cells from Duchenne muscular dystrophy. Mol Ther 18: 386-93 PMC2839293

Mizuno Y, Chang H, Umeda K, Niwa A, Iwasa T, Awaya T, Fukada S, Yamamoto H, Yamanaka S, Nakahata T, Heike T. (2010) Generation of skeletal muscle stem/progenitor cells from murine induced pluripotent stem cells. FASEB J 24: 2245-53

Nakagawa M, Takizawa N, Narita M, Ichisaka T, Yamanaka S. (2010) Promotion of direct reprogramming by transformation-deficient Myc. Proc Natl Acad Sci USA 107: 14152-7 PMC2922531

Nakagawa M, Yamanaka S. (2010) Reprogramming of somatic cells to pluripotency. Adv Exp Med Biol 695: 215-24

Nakahata T, Awaya T, Chang H, Mizuno Y, Niwa A, Fukada S, Takeda S, Yamanaka S, Heike T. (2010) Derivation of engraftable myogenic precursors from murine ES/iPS cells and generation of disease-specific iPS cells from patients with Duchenne muscular dystrophy (DMD) and other diseases. Rinsho Shinkeigaku 50: 889

Okita K, Hong H, Takahashi K, Yamanaka S. (2010) Generation of mouse-induced pluripotent stem cells with plasmid vectors. Nat Protoc 5: 418-28

Okita K, Yamanaka S. (2010) Induction of pluripotency by defined factors. Exp Cell Res 316: 2565-70

Sato S, Yagi S, Arai Y, Hirabayashi K, Hattori N, Iwatani M, Okita K, Ohgane J, Tanaka S, Wakayama T, Yamanaka S, Shiota K. (2010) Genome-wide DNA methylation profile of tissue-dependent and differentially methylated regions (T-DMRs) residing in mouse pluripotent stem cells. Genes Cells 15: 607-18

Saunders LR, Sharma AD, Tawney J, Nakagawa M, Okita K, Yamanaka S, Willenbring H, Verdin E. (2010) miRNAs regulate SIRT1 expression during mouse embryonic stem cell differentiation and in adult mouse tissues. Aging (Albany NY) 2: 415-31 PMC2933889

Takayama N, Nishimura S, Nakamura S, Shimizu T, Ohnishi R, Endo H, Yamaguchi T, Otsu M, Nishimura K, Nakanishi M, Sawaguchi A, Nagai R, Takahashi K, Yamanaka S, Nakauchi H, Eto K. (2010) Transient activation of c-MYC expression is critical for efficient platelet generation from human induced pluripotent stem cells. J Exp Med 207: 2817-30 PMC3005234

Tamaoki N, Takahashi K, Tanaka T, Ichisaka T, Aoki H, Takeda-Kawaguchi T, Iida K, Kunisada T, Shibata T, Yamanaka S, Tezuka K. (2010) Dental pulp cells for induced pluripotent stem cell banking. J Dent Res 89: 773-8

Tsuji O, Miura K, Okada Y, Fujiyoshi K, Mukaino M, Nagoshi N, Kitamura K, Kumagai G, Nishino M, Tomisato S, Higashi H, Nagai T, Katoh H, Kohda K, Matsuzaki Y, Yuzaki M, Ikeda E, Toyama Y, Nakamura M, Yamanaka S, Okano H. (2010) Therapeutic potential of appropriately evaluated safe-induced pluripotent stem cells for spinal cord injury. Proc Natl Acad Sci USA 107: 12704-9 PMC2906548

Yamanaka S. (2010) An interview with... Shinya Yamanaka. Interview by Mary Muers. Nat Rev Genet 11: 390

Yamanaka S. (2010) Patient-specific pluripotent stem cells become even more accessible. Cell Stem Cell 7: 1-2

Yamanaka S, Blau HM. (2010) Nuclear reprogramming to a pluripotent state by three approaches. Nature 465: 704-12 PMC2901154

Yoshida Y, Yamanaka S. (2010) Recent stem cell advances: induced pluripotent stem cells for disease modeling and stem cell-based regeneration. Circulation 122: 80-7

2009
Aiba K, Nedorezov T, Piao Y, Nishiyama A, Matoba R, Sharova LV, Sharov AA, Yamanaka S, Niwa H, Ko MS. (2009) Defining developmental potency and cell lineage trajectories by expression profiling of differentiating mouse embryonic stem cells. DNA Res 16: 73-80 PMC2644347

Daley GQ, Lensch MW, Jaenisch R, Meissner A, Plath K, Yamanaka S. (2009) Broader implications of defining standards for the pluripotency of iPSCs. Cell Stem Cell 4: 200-1; author reply 202

Hirami Y, Osakada F, Takahashi K, Okita K, Yamanaka S, Ikeda H, Yoshimura N, Takahashi M. (2009) Generation of retinal cells from mouse and human induced pluripotent stem cells. Neurosci Lett 458: 126-31

Hong H, Takahashi K, Ichisaka T, Aoi T, Kanagawa O, Nakagawa M, Okita K, Yamanaka S. (2009) Suppression of induced pluripotent stem cell generation by the p53-p21 pathway. Nature 460: 1132-5 PMC2917235

Iwawaki T, Akai R, Yamanaka S, Kohno K. (2009) Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability. Proc Natl Acad Sci USA 106: 16657-62 PMC2757843

Izpisua Belmonte JC, Ellis J, Hochedlinger K, Yamanaka S. (2009) Induced pluripotent stem cells and reprogramming: seeing the science through the hype. Nat Rev Genet 10: 878-83

Miura K, Okada Y, Aoi T, Okada A, Takahashi K, Okita K, Nakagawa M, Koyanagi M, Tanabe K, Ohnuki M, Ogawa D, Ikeda E, Okano H, Yamanaka S. (2009) Variation in the safety of induced pluripotent stem cell lines. Nat Biotechnol 27: 743-5

Nagata S, Toyoda M, Yamaguchi S, Hirano K, Makino H, Nishino K, Miyagawa Y, Okita H, Kiyokawa N, Nakagawa M, Yamanaka S, Akutsu H, Umezawa A, Tada T. (2009) Efficient reprogramming of human and mouse primary extra-embryonic cells to pluripotent stem cells. Genes Cells 14: 1395-404

Nakamura K, Salomonis N, Tomoda K, Yamanaka S, Conklin BR. (2009) G(i)-coupled GPCR signaling controls the formation and organization of human pluripotent colonies. PLoS One 4: e7780 PMC2777408

Nishimura K, Nakagawa T, Ono K, Ogita H, Sakamoto T, Yamamoto N, Okita K, Yamanaka S, Ito J. (2009) Transplantation of mouse induced pluripotent stem cells into the cochlea. Neuroreport 20: 1250-4

Niwa A, Umeda K, Chang H, Saito M, Okita K, Takahashi K, Nakagawa M, Yamanaka S, Nakahata T, Heike T. (2009) Orderly hematopoietic development of induced pluripotent stem cells via Flk-1(+) hemoangiogenic progenitors. J Cell Physiol 221: 367-77

Ohnuki M, Takahashi K, Yamanaka S. (2009) Generation and characterization of human induced pluripotent stem cells. Curr Protoc Stem Cell Biol Chapter 4: Unit 4A 2

Okano H, Yamanaka S, Tsuji S. (2009) [Possibility of iPS cells (discussion)]. Brain Nerve 61: 711-8

Senju S, Haruta M, Matsunaga Y, Fukushima S, Ikeda T, Takahashi K, Okita K, Yamanaka S, Nishimura Y. (2009) Characterization of dendritic cells and macrophages generated by directed differentiation from mouse induced pluripotent stem cells. Stem Cells 27: 1021-31

Silva J, Nichols J, Theunissen TW, Guo G, van Oosten AL, Barrandon O, Wray J, Yamanaka S, Chambers I, Smith A. (2009) Nanog is the gateway to the pluripotent ground state. Cell 138: 722-37 PMC3437554

Takahashi K, Narita M, Yokura M, Ichisaka T, Yamanaka S. (2009) Human induced pluripotent stem cells on autologous feeders. PLoS One 4: e8067 PMC2780725

Tanaka T, Tohyama S, Murata M, Nomura F, Kaneko T, Chen H, Hattori F, Egashira T, Seki T, Ohno Y, Koshimizu U, Yuasa S, Ogawa S, Yamanaka S, Yasuda K, Fukuda K. (2009) In vitro pharmacologic testing using human induced pluripotent stem cell-derived cardiomyocytes. Biochem Biophys Res Commun 385: 497-502

Tanaka Y, Ikeda T, Kishi Y, Masuda S, Shibata H, Takeuchi K, Komura M, Iwanaka T, Muramatsu S, Kondo Y, Takahashi K, Yamanaka S, Hanazono Y. (2009) ERas is expressed in primate embryonic stem cells but not related to tumorigenesis. Cell Transplant 18: 381-9

Taura D, Noguchi M, Sone M, Hosoda K, Mori E, Okada Y, Takahashi K, Homma K, Oyamada N, Inuzuka M, Sonoyama T, Ebihara K, Tamura N, Itoh H, Suemori H, Nakatsuji N, Okano H, Yamanaka S, Nakao K. (2009) Adipogenic differentiation of human induced pluripotent stem cells: comparison with that of human embryonic stem cells. FEBS Lett 583: 1029-33

Taura D, Sone M, Homma K, Oyamada N, Takahashi K, Tamura N, Yamanaka S, Nakao K. (2009) Induction and isolation of vascular cells from human induced pluripotent stem cells--brief report. Arterioscler Thromb Vasc Biol 29: 1100-3

Tsubooka N, Ichisaka T, Okita K, Takahashi K, Nakagawa M, Yamanaka S. (2009) Roles of Sall4 in the generation of pluripotent stem cells from blastocysts and fibroblasts. Genes Cells 14: 683-94

Yamanaka S. (2009) Ekiden to iPS Cells. Nat Med 15: 1145-8

Yamanaka S. (2009) Elite and stochastic models for induced pluripotent stem cell generation. Nature 460: 49-52

Yamanaka S. (2009) A fresh look at iPS cells. Cell 137: 13-7

Yokoo N, Baba S, Kaichi S, Niwa A, Mima T, Doi H, Yamanaka S, Nakahata T, Heike T. (2009) The effects of cardioactive drugs on cardiomyocytes derived from human induced pluripotent stem cells. Biochem Biophys Res Commun 387: 482-8

Yoshida Y, Takahashi K, Okita K, Ichisaka T, Yamanaka S. (2009) Hypoxia enhances the generation of induced pluripotent stem cells. Cell Stem Cell 5: 237-41

2008
Aoi T, Yae K, Nakagawa M, Ichisaka T, Okita K, Takahashi K, Chiba T, Yamanaka S. (2008) Generation of pluripotent stem cells from adult mouse liver and stomach cells. Science 321: 699-702

Nakagawa M, Koyanagi M, Tanabe K, Takahashi K, Ichisaka T, Aoi T, Okita K, Mochiduki Y, Takizawa N, Yamanaka S. (2008) Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat Biotechnol 26: 101-6

Narazaki G, Uosaki H, Teranishi M, Okita K, Kim B, Matsuoka S, Yamanaka S, Yamashita JK. (2008) Directed and systematic differentiation of cardiovascular cells from mouse induced pluripotent stem cells. Circulation 118: 498-506

Okita K, Ichisaka T, Yamanaka S. (2008) Establishment of mouse induced pluripotent stem cells selected for Nanog expression. Inflammation and Regeneration 28: 96–99

Okita K, Nakagawa M, Hyenjong H, Ichisaka T, Yamanaka S. (2008) Generation of mouse induced pluripotent stem cells without viral vectors. Science 322: 949-53

Yamanaka S. (2008) Symposium: Nuclear reprogramming and the control of differentiation in mammalian embryos. Introduction. Reprod Biomed Online 16: 11-2

Yamanaka S. (2008) Pluripotency and nuclear reprogramming. Philos Trans R Soc Lond B Biol Sci 363: 2079-87 PMC2610180

Yamanaka S. (2008) Induction of pluripotent stem cells from mouse fibroblasts by four transcription factors. Cell Prolif 41 Suppl 1: 51-6

2007
Hyun I, Hochedlinger K, Jaenisch R, Yamanaka S. (2007) New advances in iPS cell research do not obviate the need for human embryonic stem cells. Cell Stem Cell 1: 367-8

Lewitzky M, Yamanaka S. (2007) Reprogramming somatic cells towards pluripotency by defined factors. Curr Opin Biotechnol 18: 467-73

Okita K, Ichisaka T, Yamanaka S. (2007) Generation of germline-competent induced pluripotent stem cells. Nature 448: 313-7

Takahashi K, Okita K, Nakagawa M, Yamanaka S. (2007) Induction of pluripotent stem cells from fibroblast cultures. Nat Protoc 2: 3081-9

Takahashi K, Tanabe K, Ohnuki M, Narita M, Ichisaka T, Tomoda K, Yamanaka S. (2007) Induction of pluripotent stem cells from adult human fibroblasts by defined factors. Cell 131: 861-72

Uemoto Y, Suzuki S, Terada N, Ohno N, Ohno S, Yamanaka S, Komada M. (2007) Specific role of the truncated betaIV-spectrin Sigma6 in sodium channel clustering at axon initial segments and nodes of ranvier. J Biol Chem 282: 6548-55

Yamanaka S. (2007) Strategies and new developments in the generation of patient-specific pluripotent stem cells. Cell Stem Cell 1: 39-49

Yoshikane N, Nakamura N, Ueda R, Ueno N, Yamanaka S, Nakamura M. (2007) Drosophila NAT1, a homolog of the vertebrate translational regulator NAT1/DAP5/p97, is required for embryonic germband extension and metamorphosis. Dev Growth Differ 49: 623-34

2006
Amano H, Itakura K, Maruyama M, Ichisaka T, Nakagawa M, Yamanaka S. (2006) Identification and targeted disruption of the mouse gene encoding ESG1 (PH34/ECAT2/DPPA5). BMC Dev Biol 6: 11 PMC1420271

Imamura M, Miura K, Iwabuchi K, Ichisaka T, Nakagawa M, Lee J, Kanatsu-Shinohara M, Shinohara T, Yamanaka S. (2006) Transcriptional repression and DNA hypermethylation of a small set of ES cell marker genes in male germline stem cells. BMC Dev Biol 6: 34 PMC1564388

Okita K, Yamanaka S. (2006) Intracellular signaling pathways regulating pluripotency of embryonic stem cells. Curr Stem Cell Res Ther 1: 103-11

Takahashi K, Ichisaka T, Yamanaka S. (2006) Identification of genes involved in tumor-like properties of embryonic stem cells. Methods Mol Biol 329: 449-58

Takahashi K, Yamanaka S. (2006) Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 126: 663-76

Tokuzawa Y, Maruyama M, Yamanaka S. (2006) Utilization of digital differential display to identify novel targets of Oct3/4. Methods Mol Biol 329: 223-31

Yamanaka S. (2006) [Molecular mechanisms underlying pluripotency of embryonic stem cells]. Seikagaku 78: 27-33

Yamanaka S, Takahashi K. (2006) [Induction of pluripotent stem cells from mouse fibroblast cultures]. Tanpakushitsu Kakusan Koso 51: 2346-51

2005
Maruyama M, Ichisaka T, Nakagawa M, Yamanaka S. (2005) Differential roles for Sox15 and Sox2 in transcriptional control in mouse embryonic stem cells. J Biol Chem 280: 24371-9

Nakagawa M, Yamanaka S. (2005) [Mechanism for maintaining pluripotency in embryonic stem cells and inner cell mass]. Tanpakushitsu Kakusan Koso 50: 546-50

Takahashi K, Maruyama M, Tokuzawa Y, Murakami M, Oda Y, Yoshikane N, Makabe KW, Ichisaka T, Yamanaka S. (2005) Evolutionarily conserved non-AUG translation initiation in NAT1/p97/DAP5 (EIF4G2). Genomics 85: 360-71

Takahashi K, Murakami M, Yamanaka S. (2005) Role of the phosphoinositide 3-kinase pathway in mouse embryonic stem (ES) cells. Biochem Soc Trans 33: 1522-5

Takahashi K, Nakagawa M, Young SG, Yamanaka S. (2005) Differential membrane localization of ERas and Rheb, two Ras-related proteins involved in the phosphatidylinositol 3-kinase/mTOR pathway. J Biol Chem 280: 32768-74

Wang X, Beugnet A, Murakami M, Yamanaka S, Proud CG. (2005) Distinct signaling events downstream of mTOR cooperate to mediate the effects of amino acids and insulin on initiation factor 4E-binding proteins. Mol Cell Biol 25: 2558-72 PMC1061630

2004
Hamazaki T, Oka M, Yamanaka S, Terada N. (2004) Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation. J Cell Sci 117: 5681-6

Mak W, Nesterova TB, de Napoles M, Appanah R, Yamanaka S, Otte AP, Brockdorff N. (2004) Reactivation of the paternal X chromosome in early mouse embryos. Science 303: 666-9

Matsuda E, Shigeoka T, Iida R, Yamanaka S, Kawaichi M, Ishida Y. (2004) Expression profiling with arrays of randomly disrupted genes in mouse embryonic stem cells leads to in vivo functional analysis. Proc Natl Acad Sci USA 101: 4170-4 PMC384713

Murakami M, Ichisaka T, Maeda M, Oshiro N, Hara K, Edenhofer F, Kiyama H, Yonezawa K, Yamanaka S. (2004) mTOR is essential for growth and proliferation in early mouse embryos and embryonic stem cells. Mol Cell Biol 24: 6710-8 PMC444840

Tomoda K, Yoneda-Kato N, Fukumoto A, Yamanaka S, Kato JY. (2004) Multiple functions of Jab1 are required for early embryonic development and growth potential in mice. J Biol Chem 279: 43013-8

Yamanaka S. (2004) [Signaling maintaining pluripotency in ES cells]. Tanpakushitsu Kakusan Koso 49: 704-9

2003
Asai T, Nakatani T, Tamada S, Kuwabara N, Yamanaka S, Tashiro K, Nakao T, Komiya T, Okamura M, Kim S, Iwao H, Miura K. (2003) Activation of transcription factors AP-1 and NF-kappaB in chronic cyclosporine A nephrotoxicity: role in beneficial effects of magnesium supplementation. Transplantation 75: 1040-4

Mitsui K, Tokuzawa Y, Itoh H, Segawa K, Murakami M, Takahashi K, Maruyama M, Maeda M, Yamanaka S. (2003) The homeoprotein Nanog is required for maintenance of pluripotency in mouse epiblast and ES cells. Cell 113: 631-42

Takahashi K, Mitsui K, Yamanaka S. (2003) Role of ERas in promoting tumour-like properties in mouse embryonic stem cells. Nature 423: 541-5

Tamada S, Nakatani T, Asai T, Tashiro K, Komiya T, Sumi T, Okamura M, Kim S, Iwao H, Kishimoto T, Yamanaka S, Miura K. (2003) Inhibition of nuclear factor-kappaB activation by pyrrolidine dithiocarbamate prevents chronic FK506 nephropathy. Kidney Int 63: 306-14

Tokuzawa Y, Kaiho E, Maruyama M, Takahashi K, Mitsui K, Maeda M, Niwa H, Yamanaka S. (2003) Fbx15 is a novel target of Oct3/4 but is dispensable for embryonic stem cell self-renewal and mouse development. Mol Cell Biol 23: 2699-708 PMC152544

2002
Asai T, Nakatani T, Yamanaka S, Tamada S, Kishimoto T, Tashiro K, Nakao T, Okamura M, Kim S, Iwao H, Miura K. (2002) Magnesium supplementation prevents experimental chronic cyclosporine a nephrotoxicity via renin-angiotensin system independent mechanism. Transplantation 74: 784-91

Miura K, Nakatani T, Asai T, Yamanaka S, Tamada S, Tashiro K, Kim S, Okamura M, Iwao H. (2002) Role of hypomagnesemia in chronic cyclosporine nephropathy. Transplantation 73: 340-7

2001
Taniguchi M, Miura K, Iwao H, Yamanaka S. (2001) Quantitative assessment of DNA microarrays--comparison with Northern blot analyses. Genomics 71: 34-9

2000
Miura K, Yamanaka S, Ebara T, Okumura M, Imanishi M, Kim S, Nakatani T, Iwao H. (2000) Effects of nitric oxide scavenger, carboxy-PTIO on endotoxin-induced alterations in systemic hemodynamics in rats. Jpn J Pharmacol 82: 261-4

Nakamura Y, Miura K, Fujino Y, Iwao H, Ogita S, Yamanaka S. (2000) Evolution, structure, and expression of GNPI/Oscillin orthologous genes. Genomics 68: 179-86

Yamanaka S, Zhang XY, Maeda M, Miura K, Wang S, Farese RV, Jr., Iwao H, Innerarity TL. (2000) Essential role of NAT1/p97/DAP5 in embryonic differentiation and the retinoic acid pathway. EMBO J 19: 5533-41 PMC314019

1999
Hamaguchi A, Kim S, Izumi Y, Zhan Y, Yamanaka S, Iwao H. (1999) Contribution of extracellular signal-regulated kinase to angiotensin II-induced transforming growth factor-beta1 expression in vascular smooth muscle cells. Hypertension 34: 126-31

Miura K, Okumura M, Yamanaka S, Kim S, Iwao H. (1999) No participation of adenosine A1 receptor in acute nephrotoxicity by 4-pentenoic acid administration in dogs. Jpn J Pharmacol 80: 223-8

Miura K, Okumura M, Yamanaka S, Kim S, Iwao H. (1999) Effects of activation of renal adenosine A2 receptor on renal function and renin release in dogs. Jpn J Pharmacol 80: 173-6

1998
Hamaguchi A, Kim S, Yano M, Yamanaka S, Iwao H. (1998) Activation of glomerular mitogen-activated protein kinases in angiotensin II-mediated hypertension. J Am Soc Nephrol 9: 372-80

Izumi Y, Kim S, Murakami T, Yamanaka S, Iwao H. (1998) Cardiac mitogen-activated protein kinase activities are chronically increased in stroke-prone hypertensive rats. Hypertension 31: 50-6

Kim S, Izumi Y, Yano M, Hamaguchi A, Miura K, Yamanaka S, Miyazaki H, Iwao H. (1998) Angiotensin blockade inhibits activation of mitogen-activated protein kinases in rat balloon-injured artery. Circulation 97: 1731-7

Qian X, Balestra ME, Yamanaka S, Boren J, Lee I, Innerarity TL. (1998) Low expression of the apolipoprotein B mRNA-editing transgene in mice reduces LDL levels but does not cause liver dysplasia or tumors. Arterioscler Thromb Vasc Biol 18: 1013-20

Seto M, Kim S, Yoshifusa H, Nakamura Y, Masuda T, Hamaguchi A, Yamanaka S, Iwao H. (1998) Effects of prednisolone on glomerular signal transduction cascades in experimental glomerulonephritis. J Am Soc Nephrol 9: 1367-76

Uchida J, Miura K, Yamanaka S, Kim S, Iwao H, Nakatani T, Kishimoto T. (1998) Renal endothelin in FK506-induced nephrotoxicity in spontaneously hypertensive rats. Jpn J Pharmacol 76: 39-49

Yamanaka S, Zhang XY, Miura K, Kim S, Iwao H. (1998) The human gene encoding the lectin-type oxidized LDL receptor (OLR1) is a novel member of the natural killer gene complex with a unique expression profile. Genomics 54: 191-9

Yano M, Kim S, Izumi Y, Yamanaka S, Iwao H. (1998) Differential activation of cardiac c-jun amino-terminal kinase and extracellular signal-regulated kinase in angiotensin II-mediated hypertension. Circ Res 83: 752-60

1997
Kim S, Murakami T, Izumi Y, Yano M, Miura K, Yamanaka S, Iwao H. (1997) Extracellular signal-regulated kinase and c-Jun NH2-terminal kinase activities are continuously and differentially increased in aorta of hypertensive rats. Biochem Biophys Res Commun 236: 199-204

Kim S, Sada T, Mizuno M, Ikeda M, Yano M, Miura K, Yamanaka S, Koike H, Iwao H. (1997) Effects of angiotensin AT1 receptor antagonist on volume overload-induced cardiac gene expression in rats. Hypertens Res 20: 133-42

Kim S, Wanibuchi H, Hamaguchi A, Miura K, Yamanaka S, Iwao H. (1997) Angiotensin blockade improves cardiac and renal complications of type II diabetic rats. Hypertension 30: 1054-61

Matsuura T, Miura K, Ebara T, Yukimura T, Yamanaka S, Kim S, Iwao H. (1997) Renal vascular effects of the selective endothelin receptor antagonists in anaesthetized rats. Br J Pharmacol 122: 81-6 PMC1564907

Yamanaka S, Iwao H. (1997) [RNA editing]. Tanpakushitsu Kakusan Koso 42: 803-11

Yamanaka S, Poksay KS, Arnold KS, Innerarity TL. (1997) A novel translational repressor mRNA is edited extensively in livers containing tumors caused by the transgene expression of the apoB mRNA-editing enzyme. Genes Dev 11: 321-33

1996
Innerarity TL, Boren J, Yamanaka S, Olofsson SO. (1996) Biosynthesis of apolipoprotein B48-containing lipoproteins. Regulation by novel post-transcriptional mechanisms. J Biol Chem 271: 2353-6

Yamanaka S, Poksay KS, Driscoll DM, Innerarity TL. (1996) Hyperediting of multiple cytidines of apolipoprotein B mRNA by APOBEC-1 requires auxiliary protein(s) but not a mooring sequence motif. J Biol Chem 271: 11506-10

1995
Yamanaka S, Balestra ME, Ferrell LD, Fan J, Arnold KS, Taylor S, Taylor JM, Innerarity TL. (1995) Apolipoprotein B mRNA-editing protein induces hepatocellular carcinoma and dysplasia in transgenic animals. Proc Natl Acad Sci USA 92: 8483-7 PMC41181

1994
Yamanaka S, Poksay KS, Balestra ME, Zeng GQ, Innerarity TL. (1994) Cloning and mutagenesis of the rabbit ApoB mRNA editing protein. A zinc motif is essential for catalytic activity, and noncatalytic auxiliary factor(s) of the editing complex are widely distributed. J Biol Chem 269: 21725-34

1993
Yamanaka S, Iwao H, Yukimura T, Kim S, Miura K. (1993) Effect of the platelet-activating factor antagonist, TCV-309, and the cyclo-oxygenase inhibitor, ibuprofen, on the haemodynamic changes in canine experimental endotoxic shock. Br J Pharmacol 110: 1501-7 PMC2175868

Yamanaka S, Iwao H, Yukimura T, Kim S, Miura K. (1993) Effect of NG-nitro-L-arginine on effective vascular stiffness in dogs. Jpn J Pharmacol 63: 41-5

Yamanaka S, Miura K, Yukimura T, Yamamoto K. (1993) 11-Dehydro thromboxane B2: a reliable parameter of thromboxane A2 production in dogs. Prostaglandins 45: 221-8

1992
Yukimura T, Miura K, Yamashita Y, Shimmen T, Okumura M, Yamanaka S, Saito M, Yamamoto K. (1991) Effects of the calcium channel antagonist nicardipine on renal action of endothelin in dogs. Contrib Nephrol 90: 105-10

Yamanaka S, Miura K, Yukimura T, Okumura M, Yamamoto K. (1992) Putative mechanism of hypotensive action of platelet-activating factor in dogs. Circ Res 70: 893-901

Yukimura T, Yamashita Y, Miura K, Okumura M, Yamanaka S, Yamamoto K. (1992) Renal effects of the nitric oxide synthase inhibitor, L-NG-nitroarginine, in dogs. Am J Hypertens 5: 484-7

1991
Miura K, Yukimura T, Yamashita Y, Shimmen T, Okumura M, Yamanaka S, Imanishi M, Yamamoto K. (1991) Renal and femoral vascular responses to endothelin-1 in dogs: role of prostaglandins. J Pharmacol Exp Ther 256: 11-7

Yamashita Y, Yukimura T, Miura K, Okumura M, Yamanaka S, Yamamoto K. (1991) Effects of NG-nitro-L-arginine on renal hemodynamic responses to endothelin-3 in anesthetized dogs. J Cardiovasc Pharmacol 17 Suppl 7: S332-4

1990
Miura K, Yukimura T, Yamashita Y, Shichino K, Shimmen T, Saito M, Okumura M, Imanishi M, Yamanaka S, Yamamoto K. (1990) Effects of endothelin on renal hemodynamics and renal function in anesthetized dogs. Am J Hypertens 3: 632-4